Infection of human intestinal epithelial cells by invasive bacteria activates NF-κB and increases ICAM-1 expression through NOD1

BACKGROUND/AIMS: Nucleotide-binding oligomerization domain 1 (NOD1) is required for primary intestinal epithelial cells (IECs) to respond to natural mucopeptides secreted by gram-negative bacteria. Infection of human IECs with invasive bacteria up-regulates intercellular adhesion molecule-1 (ICAM-1)...

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Bibliographic Details
Published in:Korean J Intern Med
Main Authors: Shin, Woon Geon, Park, Bum Joon, Lee, Sung Joong, Kim, Jae Gyu
Format: Artigo
Language:Inglês
Published: The Korean Association of Internal Medicine 2018
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5768537/
https://ncbi.nlm.nih.gov/pubmed/28092699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3904/kjim.2015.409
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