The glucose and lipid metabolism reprogramming is grade-dependent in clear cell renal cell carcinoma primary cultures and is targetable to modulate cell viability and proliferation

Clear cell renal cell carcinoma (ccRCC) has a poor prognosis despite novel biological targeted therapies. Tumor aggressiveness and poor survival may correlate with tumor grade at diagnosis and with complex metabolic alterations, also involving glucose and lipid metabolism. However, currently no grad...

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Vydáno v:Oncotarget
Hlavní autoři: Bianchi, Cristina, Meregalli, Chiara, Bombelli, Silvia, Di Stefano, Vitalba, Salerno, Francesco, Torsello, Barbara, De Marco, Sofia, Bovo, Giorgio, Cifola, Ingrid, Mangano, Eleonora, Battaglia, Cristina, Strada, Guido, Lucarelli, Giuseppe, Weiss, Robert H., Perego, Roberto A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2017
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5768342/
https://ncbi.nlm.nih.gov/pubmed/29371925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.23056
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