The glucose and lipid metabolism reprogramming is grade-dependent in clear cell renal cell carcinoma primary cultures and is targetable to modulate cell viability and proliferation

Clear cell renal cell carcinoma (ccRCC) has a poor prognosis despite novel biological targeted therapies. Tumor aggressiveness and poor survival may correlate with tumor grade at diagnosis and with complex metabolic alterations, also involving glucose and lipid metabolism. However, currently no grad...

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Veröffentlicht in:Oncotarget
Hauptverfasser: Bianchi, Cristina, Meregalli, Chiara, Bombelli, Silvia, Di Stefano, Vitalba, Salerno, Francesco, Torsello, Barbara, De Marco, Sofia, Bovo, Giorgio, Cifola, Ingrid, Mangano, Eleonora, Battaglia, Cristina, Strada, Guido, Lucarelli, Giuseppe, Weiss, Robert H., Perego, Roberto A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2017
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5768342/
https://ncbi.nlm.nih.gov/pubmed/29371925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.23056
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