Hypermethylation of BEND5 contributes to cell proliferation and is a prognostic marker of colorectal cancer

Aberrant hypermethylation of CpG islands in tumor suppressor genes (TSGs) contributes to colorectal tumorigenesis. To identify new colorectal cancer (CRC) screening marker, we investigated DNA methylation alterations in novel TSGs. Using HumanMethylation450 BeadChip arrays, CpG regions in BEND5 were...

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Bibliographic Details
Published in:Oncotarget
Main Authors: Lin, Ruo-Kai, Hung, Wan-Yu, Huang, Yu-Fang, Chang, Yu-Jia, Lin, Chien-Hsing, Chen, Wei-Yu, Chiu, Shih-Feng, Chang, Shih-Ching, Tsai, Shih-Feng
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2017
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5768337/
https://ncbi.nlm.nih.gov/pubmed/29371920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.22266
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