Hypermethylation of BEND5 contributes to cell proliferation and is a prognostic marker of colorectal cancer

Aberrant hypermethylation of CpG islands in tumor suppressor genes (TSGs) contributes to colorectal tumorigenesis. To identify new colorectal cancer (CRC) screening marker, we investigated DNA methylation alterations in novel TSGs. Using HumanMethylation450 BeadChip arrays, CpG regions in BEND5 were...

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Udgivet i:Oncotarget
Main Authors: Lin, Ruo-Kai, Hung, Wan-Yu, Huang, Yu-Fang, Chang, Yu-Jia, Lin, Chien-Hsing, Chen, Wei-Yu, Chiu, Shih-Feng, Chang, Shih-Ching, Tsai, Shih-Feng
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2017
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Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5768337/
https://ncbi.nlm.nih.gov/pubmed/29371920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.22266
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