Ring finger protein 126 (RNF126) suppresses ionizing radiation–induced p53-binding protein 1 (53BP1) focus formation

Cells have evolved sophisticated mechanisms to maintain genomic integrity in response to DNA damage. Ionizing radiation (IR)–induced DNA damage results in the formation of IR-induced foci (iRIF) in the nucleus. The iRIF formation is part of the DNA damage response (DDR), which is an essential signal...

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Vydáno v:J Biol Chem
Hlavní autoři: Lee, Nam Soo, Chang, Hae Ryung, Kim, Soomi, Ji, Jae-Hoon, Lee, Joorak, Lee, Hyun Ji, Seo, Yoojeong, Kang, Misun, Han, Joo Seok, Myung, Kyungjae, Kim, Yonghwan, Kim, Hongtae
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2018
Témata:
Signal Transduction
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5767864/
https://ncbi.nlm.nih.gov/pubmed/29167269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.765602
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