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Genetic screening of regulatory regions of pituitary transcription factors in patients with idiopathic pituitary hormone deficiencies

PURPOSE: Mutation frequencies of PROP1, POU1F1 and HESX1 in patients with combined pituitary hormone deficiencies (CPHD) vary substantially between populations. They are low in sporadic CPHD patients in Western Europe. However, most clinicians still routinely send DNA of their CPHD patients for gene...

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Bibliografiske detaljer
Udgivet i:Pituitary
Main Authors: Elizabeth, Melitza, Hokken-Koelega, Anita C. S., Schuilwerve, Joyce, Peeters, Robin P., Visser, Theo J., de Graaff, Laura C. G.
Format: Artigo
Sprog:Inglês
Udgivet: Springer US 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5767207/
https://ncbi.nlm.nih.gov/pubmed/29255988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11102-017-0850-6
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