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Genetic analysis of IRF6, a gene involved in craniofacial midline formation, in relation to pituitary and facial morphology of patients with idiopathic growth hormone deficiency

INTRODUCTION: Growth hormone is secreted by the pituitary gland, which forms part of the craniofacial midline. IRF6 encodes a transcription factor involved in the development of the craniofacial midline and mutations in IRF6 are known to disturb craniofacial development. Craniofacial and pituitary d...

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Detalhes bibliográficos
Publicado no:Pituitary
Main Authors: Starink, Eline, Hokken-Koelega, Anita C. S., Visser, Theo J., Baan, Janneke, Peeters, Robin P., de Graaff, Laura C. G.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5606942/
https://ncbi.nlm.nih.gov/pubmed/28593555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11102-017-0808-8
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