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Craniofacial Ciliopathies Reveal Specific Requirements for GLI Proteins during Development of the Facial Midline

Ciliopathies represent a broad class of disorders that affect multiple organ systems. The craniofacial complex is among those most severely affected when primary cilia are not functional. We previously reported that loss of primary cilia on cranial neural crest cells, via a conditional knockout of t...

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Publicado en:PLoS Genet
Autores principales: Chang, Ching-Fang, Chang, Ya-Ting, Millington, Grethel, Brugmann, Samantha A.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5089743/
https://ncbi.nlm.nih.gov/pubmed/27802276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1006351
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