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The peptidyl-prolyl isomerase PIN1 relieves cyclin-dependent kinase 2 (CDK2) inhibition by the CDK inhibitor p27

PIN1 is a peptidyl-prolyl isomerase that catalyzes the cis/trans isomerization of peptide bonds between proline and phosphorylated serine/threonine residues. By changing the conformation of its protein substrates, PIN1 increases the activities of key proteins that promote cell cycle progression and...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Cheng, Chi-Wai, Leong, Ka-Wai, Ng, Yiu-Ming, Kwong, Yok-Lam, Tse, Eric
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5766953/
https://ncbi.nlm.nih.gov/pubmed/29118189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.801373
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