Interferon regulatory factor 5 (IRF5) suppresses hepatitis C virus (HCV) replication and HCV-associated hepatocellular carcinoma

Hepatitis C virus (HCV) infection is a major risk factor for the development of chronic liver disease. The disease typically progresses from chronic HCV to fibrosis, cirrhosis, hepatocellular carcinoma (HCC), and death. Chronic inflammation associated with HCV infection is implicated in cirrhosis an...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Cevik, Ozge, Li, Dan, Baljinnyam, Erdene, Manvar, Dinesh, Pimenta, Erica M., Waris, Gulam, Barnes, Betsy J., Kaushik-Basu, Neerja
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2017
Assuntos:
Molecular Bases of Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5766933/
https://ncbi.nlm.nih.gov/pubmed/29079574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.792721
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