Interferon regulatory factor 5 (IRF5) suppresses hepatitis C virus (HCV) replication and HCV-associated hepatocellular carcinoma

Hepatitis C virus (HCV) infection is a major risk factor for the development of chronic liver disease. The disease typically progresses from chronic HCV to fibrosis, cirrhosis, hepatocellular carcinoma (HCC), and death. Chronic inflammation associated with HCV infection is implicated in cirrhosis an...

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Détails bibliographiques
Publié dans:J Biol Chem
Auteurs principaux: Cevik, Ozge, Li, Dan, Baljinnyam, Erdene, Manvar, Dinesh, Pimenta, Erica M., Waris, Gulam, Barnes, Betsy J., Kaushik-Basu, Neerja
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2017
Sujets:
Molecular Bases of Disease
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5766933/
https://ncbi.nlm.nih.gov/pubmed/29079574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.792721
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