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The actin-organizing formin protein Fhod3 is required for postnatal development and functional maintenance of the adult heart in mice
Cardiac development and function require actin–myosin interactions in the sarcomere, a highly organized contractile structure. Sarcomere assembly mediated by formin homology 2 domain-containing 3 (Fhod3), a member of formins that directs formation of straight actin filaments, is essential for embryo...
Uloženo v:
| Vydáno v: | J Biol Chem |
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| Hlavní autoři: | , , , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society for Biochemistry and Molecular Biology
2018
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5766910/ https://ncbi.nlm.nih.gov/pubmed/29158260 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.813931 |
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