The actin-organizing formin protein Fhod3 is required for postnatal development and functional maintenance of the adult heart in mice

Cardiac development and function require actin–myosin interactions in the sarcomere, a highly organized contractile structure. Sarcomere assembly mediated by formin homology 2 domain-containing 3 (Fhod3), a member of formins that directs formation of straight actin filaments, is essential for embryo...

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Dades bibliogràfiques
Publicat a:J Biol Chem
Autors principals: Ushijima, Tomoki, Fujimoto, Noriko, Matsuyama, Sho, Kan-o, Meikun, Kiyonari, Hiroshi, Shioi, Go, Kage, Yohko, Yamasaki, Sho, Takeya, Ryu, Sumimoto, Hideki
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2018
Matèries:
Cell Biology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5766910/
https://ncbi.nlm.nih.gov/pubmed/29158260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.813931
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