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The actin-organizing formin protein Fhod3 is required for postnatal development and functional maintenance of the adult heart in mice
Cardiac development and function require actin–myosin interactions in the sarcomere, a highly organized contractile structure. Sarcomere assembly mediated by formin homology 2 domain-containing 3 (Fhod3), a member of formins that directs formation of straight actin filaments, is essential for embryo...
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| Publicado no: | J Biol Chem |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5766910/ https://ncbi.nlm.nih.gov/pubmed/29158260 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.813931 |
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