Regulation of Vegf signaling by natural and synthetic ligands

The mechanisms that allow cells to bypass anti–vascular endothelial growth factor A (VEGFA) therapy remain poorly understood. Here we use zebrafish to investigate this question and first show that vegfaa mutants display a severe vascular phenotype that can surprisingly be rescued to viability by veg...

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Bibliographic Details
Published in:Blood
Main Authors: Rossi, Andrea, Gauvrit, Sebastien, Marass, Michele, Pan, Luyuan, Moens, Cecilia B., Stainier, Didier Y. R.
Format: Artigo
Language:Inglês
Published: American Society of Hematology 2016
Subjects:
Vascular Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5766839/
https://ncbi.nlm.nih.gov/pubmed/27557946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2016-04-711192
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