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Monitoring Ca(2+) elevations in individual astrocytes upon local release of amyloid beta in acute brain slices
The pathogenesis of Alzheimer’s disease (AD) is thought to involve acute neurotoxic effects exerted by oligomeric forms of amyloid-β 1-42 (Aβ). Application of Aβ oligomers in physiological concentrations have been shown to transiently elevate internal Ca(2+) in cultured astroglia. While the cellular...
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| Publicat a: | Brain Res Bull |
|---|---|
| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Elsevier Science
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5766740/ https://ncbi.nlm.nih.gov/pubmed/28011193 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainresbull.2016.12.007 |
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