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β-Sheet Breaker Peptide-HPYD for the Treatment of Alzheimer's Disease: Primary Studies on Behavioral Test and Transcriptional Profiling

Background: Alzheimer's disease (AD), is a progressive neurodegenerative disease that is characterized by cognitive loss. Most researchers believe that aggregation and accumulation of β-amyloid peptides (Aβ) in brain cells are the central pathological hallmark of this disease. Methods: Based on...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Liu, Weiying, Sun, Fengxian, Wan, Moxin, Jiang, Fang, Bo, Xiangyu, Lin, Laixiang, Tang, Hua, Xu, Shumei
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5766670/
https://ncbi.nlm.nih.gov/pubmed/29358920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2017.00969
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