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Novel endogenous simian retroviral integrations in Vero cells: implications for quality control of a human vaccine cell substrate
African green monkey (AGM)-derived Vero cells have been utilized to produce various human vaccines. The Vero cell genome harbors a variety of simian endogenous type D retrovirus (SERV) sequences. In this study, a transcriptome analysis showed that DNA hypomethylation released the epigenetic repressi...
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| Pubblicato in: | Sci Rep |
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| Autori principali: | , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group UK
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5766633/ https://ncbi.nlm.nih.gov/pubmed/29330501 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-18934-2 |
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