Interaction of suppressor of cytokine signalling 3 with cavin-1 links SOCS3 function and cavin-1 stability

Effective suppression of JAK–STAT signalling by the inducible inhibitor “suppressor of cytokine signalling 3” (SOCS3) is essential for limiting signalling from cytokine receptors. Here we show that cavin-1, a component of caveolae, is a functionally significant SOCS3-interacting protein. Biochemical...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Williams, Jamie J. L., Alotaiq, Nasser, Mullen, William, Burchmore, Richard, Liu, Libin, Baillie, George S., Schaper, Fred, Pilch, Paul F., Palmer, Timothy M.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5766592/
https://ncbi.nlm.nih.gov/pubmed/29330478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-02585-y
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