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Virtual Genome Walking across the 32 Gb Ambystoma mexicanum genome; assembling gene models and intronic sequence

Large repeat rich genomes present challenges for assembly using short read technologies. The 32 Gb axolotl genome is estimated to contain ~19 Gb of repetitive DNA making an assembly from short reads alone effectively impossible. Indeed, this model species has been sequenced to 20× coverage but the r...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Evans, Teri, Johnson, Andrew D., Loose, Matthew
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5766544/
https://ncbi.nlm.nih.gov/pubmed/29330416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-19128-6
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