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Genomic characterization of the T-cell receptor loci in Ambystoma mexicanum

BackgroundAmphibians are valuable models for comparative immunology. In the caudate Ambystoma mexicanum, the architecture of immunoglobulin loci resembles that of the anuran Xenopus tropicalis, although some antibody gene features are absent. Evidence supports the presence of T lymphocytes in axolot...

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Autori principali: Diana L. Pacheco-Olvera, Stephanie Saint Remy-Hernández, E. Ernestina Godoy-Lozano, Juan Téllez-Sosa, Humberto Valdovinos-Torres, Everado Curiel-Quesada, Constantino López-Macías, Jesus Martínez-Barnetche
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2025-09-01
Serie:Frontiers in Immunology
Soggetti:
Ambystoma
T-cell receptor (TR)
TRA/TRD locus
TRB locus
pseudogenes
amphibians
Accesso online:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1656386/full
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