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Induction of ferroptosis and mitochondrial dysfunction by oxidative stress in PC12 cells

Neurodegenerative diseases (NDD) are typically associated with neuron loss in nervous system areas. Interventions with related death mechanisms may ameliorate NDD progression. Oxidative stress plays an important role in NDD cell death routines. However, tert-butylhydroperoxide (t-BHP), a widely used...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Wu, Chuanhong, Zhao, Wenwen, Yu, Jie, Li, Shaojing, Lin, Ligen, Chen, Xiuping
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5766540/
https://ncbi.nlm.nih.gov/pubmed/29330409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-18935-1
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