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Unique Roles of β-Arrestin in GPCR Trafficking Revealed by Photoinducible Dimerizers

Intracellular trafficking of G protein-coupled receptors (GPCRs) controls their localization and degradation, which affects a cell’s ability to adapt to extracellular stimuli. Although the perturbation of trafficking induces important diseases, these trafficking mechanisms are poorly understood. Her...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Takenouchi, Osamu, Yoshimura, Hideaki, Ozawa, Takeaki
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5766490/
https://ncbi.nlm.nih.gov/pubmed/29330504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-19130-y
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