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Redox Mechanisms Influencing cGMP Signaling in Pulmonary Vascular Physiology and Pathophysiology

The soluble form of guanylate cyclase (sGC) and cGMP signaling are major regulators of pulmonary vasodilation and vascular remodeling that protect the pulmonary circulation from hypertension development. Nitric oxide, reactive oxygen species, thiol and heme redox, and heme biosynthesis control mecha...

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Detalhes bibliográficos
Publicado no:Adv Exp Med Biol
Main Authors: Patel, Dhara, Lakhkar, Anand, Wolin, Michael S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5766272/
https://ncbi.nlm.nih.gov/pubmed/29047089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-3-319-63245-2_13
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