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Tuning RNA folding and function through rational design of junction topology

Structured RNAs such as ribozymes must fold into specific 3D structures to carry out their biological functions. While it is well-known that architectural features such as flexible junctions between helices help guide RNA tertiary folding, the mechanisms through which junctions influence folding rem...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nucleic Acids Res
Prif Awduron: Daher, May, Mustoe, Anthony M., Morriss-Andrews, Alex, Brooks III, Charles L., Walter, Nils G.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5766210/
https://ncbi.nlm.nih.gov/pubmed/28934478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx614
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