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Crystal structure of an engineered, HIV-specific recombinase for removal of integrated proviral DNA
As part of the HIV infection cycle, viral DNA inserts into the genome of host cells such that the integrated DNA encoding the viral proteins is flanked by long terminal repeat (LTR) regions from the retrovirus. In an effort to develop novel genome editing techniques that safely excise HIV provirus f...
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| Publicado no: | Nucleic Acids Res |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5766204/ https://ncbi.nlm.nih.gov/pubmed/28934476 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx603 |
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