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Crystal structure of an engineered, HIV-specific recombinase for removal of integrated proviral DNA
As part of the HIV infection cycle, viral DNA inserts into the genome of host cells such that the integrated DNA encoding the viral proteins is flanked by long terminal repeat (LTR) regions from the retrovirus. In an effort to develop novel genome editing techniques that safely excise HIV provirus f...
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| 出版年: | Nucleic Acids Res |
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| 主要な著者: | , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Oxford University Press
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5766204/ https://ncbi.nlm.nih.gov/pubmed/28934476 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx603 |
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