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Crystal structure of an engineered, HIV-specific recombinase for removal of integrated proviral DNA

As part of the HIV infection cycle, viral DNA inserts into the genome of host cells such that the integrated DNA encoding the viral proteins is flanked by long terminal repeat (LTR) regions from the retrovirus. In an effort to develop novel genome editing techniques that safely excise HIV provirus f...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Nucleic Acids Res
Egile Nagusiak: Meinke, Gretchen, Karpinski, Janet, Buchholz, Frank, Bohm, Andrew
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2017
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5766204/
https://ncbi.nlm.nih.gov/pubmed/28934476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx603
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