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In vivo probing of nascent RNA structures reveals principles of cotranscriptional folding
Defining the in vivo folding pathway of cellular RNAs is essential to understand how they reach their final native conformation. We here introduce a novel method, named Structural Probing of Elongating Transcripts (SPET-seq), that permits single-base resolution analysis of transcription intermediate...
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| Gepubliceerd in: | Nucleic Acids Res |
|---|---|
| Hoofdauteurs: | , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Oxford University Press
2017
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5766169/ https://ncbi.nlm.nih.gov/pubmed/28934475 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx617 |
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