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In vivo probing of nascent RNA structures reveals principles of cotranscriptional folding

Defining the in vivo folding pathway of cellular RNAs is essential to understand how they reach their final native conformation. We here introduce a novel method, named Structural Probing of Elongating Transcripts (SPET-seq), that permits single-base resolution analysis of transcription intermediate...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Nucleic Acids Res
Päätekijät: Incarnato, Danny, Morandi, Edoardo, Anselmi, Francesca, Simon, Lisa M., Basile, Giulia, Oliviero, Salvatore
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Oxford University Press 2017
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5766169/
https://ncbi.nlm.nih.gov/pubmed/28934475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx617
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