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In vivo probing of nascent RNA structures reveals principles of cotranscriptional folding
Defining the in vivo folding pathway of cellular RNAs is essential to understand how they reach their final native conformation. We here introduce a novel method, named Structural Probing of Elongating Transcripts (SPET-seq), that permits single-base resolution analysis of transcription intermediate...
Enregistré dans:
| Publié dans: | Nucleic Acids Res |
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| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Oxford University Press
2017
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5766169/ https://ncbi.nlm.nih.gov/pubmed/28934475 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx617 |
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