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Fingolimod and macular edema: Pathophysiology, diagnosis, and management

Fingolimod causes macular edema (ME) by acting via the S1P3 receptor agonism, thereby reducing the tight junction between the endothelial cells of the retinal capillaries. This results in the breakdown of the inner blood retinal barrier, causing ME. Ophthalmologic evaluation including optical cohere...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Neurol Clin Pract
Hauptverfasser: Cugati, Sudha, Chen, Celia S., Lake, Stewart, Lee, Andrew W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Academy of Neurology 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5765686/
https://ncbi.nlm.nih.gov/pubmed/29443255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/CPJ.0000000000000027
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