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Fingolimod and macular edema: Pathophysiology, diagnosis, and management

Fingolimod causes macular edema (ME) by acting via the S1P3 receptor agonism, thereby reducing the tight junction between the endothelial cells of the retinal capillaries. This results in the breakdown of the inner blood retinal barrier, causing ME. Ophthalmologic evaluation including optical cohere...

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Detalhes bibliográficos
Publicado no:Neurol Clin Pract
Main Authors: Cugati, Sudha, Chen, Celia S., Lake, Stewart, Lee, Andrew W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Academy of Neurology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5765686/
https://ncbi.nlm.nih.gov/pubmed/29443255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/CPJ.0000000000000027
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