Chemoselective ratiometric imaging of protein S-sulfenylation

Here we report a ratiometric fluorescent probe for chemoselective conjugation to sulfenic acids in living cells. Our approach couples an α-fluoro-substituted dimedone to an aminonaphthalene fluorophore (F-DiNap), which upon sulfenic acid conjugation is locked as the 1,3-diketone, changing the fluoro...

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發表在:Chem Commun (Camb)
Main Authors: Tom, Christopher T.M.B., Crellin, John E., Motiwala, Hashim F., Stone, Matthew B., Davda, Dahvid, Walker, William, Kuo, Yu-Hsuan, Hernandez, Jeannie L., Labby, Kristin J., Gomez-Rodriguez, Lyanne, Jenkins, Paul M., Veatch, Sarah L., Martin, Brent R.
格式: Artigo
語言:Inglês
出版: 2017
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5765544/
https://ncbi.nlm.nih.gov/pubmed/28613292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7cc02285a
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