Natural Variation in SER1 and ENA6 Underlie Condition-Specific Growth Defects in Saccharomyces cerevisiae

Despite their ubiquitous use in laboratory strains, naturally occurring loss-of-function mutations in genes encoding core metabolic enzymes are relatively rare in wild isolates of Saccharomyces cerevisiae. Here, we identify a naturally occurring serine auxotrophy in a sake brewing strain from Japan....

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Pubblicato in:G3 (Bethesda)
Autori principali: Sirr, Amy, Scott, Adrian C., Cromie, Gareth A., Ludlow, Catherine L., Ahyong, Vida, Morgan, Trey S., Gilbert, Teresa, Dudley, Aimée M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Genetics Society of America 2017
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Investigations
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5765352/
https://ncbi.nlm.nih.gov/pubmed/29138237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.117.300392
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