Prognostic impact and concordance of TERT promoter mutation and protein expression in matched primary and metastatic cutaneous melanoma

BACKGROUND: TERT promoter mutations are frequent in melanoma. Here we analysed the concordance and prognostic impact of TERT mutation and telomerase reverse transcriptase (TERT) protein expression in a large melanoma series. METHODS: In 194 primary nodular melanomas with 72 matched loco-regional met...

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Detalhes bibliográficos
Publicado no:Br J Cancer
Main Authors: Hugdahl, Emilia, Kalvenes, May Britt, Mannelqvist, Monica, Ladstein, Rita G, Akslen, Lars A
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2018
Assuntos:
Molecular Diagnostics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5765228/
https://ncbi.nlm.nih.gov/pubmed/29123258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2017.384
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