Sox5 contributes to prostate cancer metastasis and is a master regulator of TGF-β-induced epithelial mesenchymal transition through controlling Twist1 expression

BACKGROUND: Metastatic castration-resistant prostate cancer (mCRPC) is one of the main contributors to the death of prostate cancer patients. To date, the detailed molecular mechanisms underlying mCRPC are unclear. Given the crucial role of epithelial–mesenchymal transition (EMT) in cancer metastasi...

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Detalhes bibliográficos
Publicado no:Br J Cancer
Main Authors: Hu, Jieping, Tian, Jing, Zhu, Shimiao, Sun, Libin, Yu, Jianpeng, Tian, Hao, Dong, Qian, Luo, Qiang, Jiang, Ning, Niu, Yuanjie, Shang, Zhiqun
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2018
Assuntos:
Molecular Diagnostics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5765224/
https://ncbi.nlm.nih.gov/pubmed/29123266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2017.372
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