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Mapping the operational landscape of microRNAs in synthetic gene circuits

MicroRNAs are a class of short, noncoding RNAs that are ubiquitous modulators of gene expression, with roles in development, homeostasis, and disease. Engineered microRNAs are now frequently used as regulatory modules in synthetic biology. Moreover, synthetic gene circuits equipped with engineered m...

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Bibliografiske detaljer
Udgivet i:NPJ Syst Biol Appl
Main Authors: Quarton, Tyler, Ehrhardt, Kristina, Lee, James, Kannan, Srijaa, Li, Yi, Ma, Lan, Bleris, Leonidas
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5765153/
https://ncbi.nlm.nih.gov/pubmed/29354284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41540-017-0043-y
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