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Mapping the operational landscape of microRNAs in synthetic gene circuits

MicroRNAs are a class of short, noncoding RNAs that are ubiquitous modulators of gene expression, with roles in development, homeostasis, and disease. Engineered microRNAs are now frequently used as regulatory modules in synthetic biology. Moreover, synthetic gene circuits equipped with engineered m...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:NPJ Syst Biol Appl
Hauptverfasser: Quarton, Tyler, Ehrhardt, Kristina, Lee, James, Kannan, Srijaa, Li, Yi, Ma, Lan, Bleris, Leonidas
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5765153/
https://ncbi.nlm.nih.gov/pubmed/29354284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41540-017-0043-y
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