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Mapping the operational landscape of microRNAs in synthetic gene circuits

MicroRNAs are a class of short, noncoding RNAs that are ubiquitous modulators of gene expression, with roles in development, homeostasis, and disease. Engineered microRNAs are now frequently used as regulatory modules in synthetic biology. Moreover, synthetic gene circuits equipped with engineered m...

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Detalhes bibliográficos
Publicado no:NPJ Syst Biol Appl
Main Authors: Quarton, Tyler, Ehrhardt, Kristina, Lee, James, Kannan, Srijaa, Li, Yi, Ma, Lan, Bleris, Leonidas
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5765153/
https://ncbi.nlm.nih.gov/pubmed/29354284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41540-017-0043-y
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