Impaired autophagy bridges lysosomal storage disease and epithelial dysfunction in the kidney

The endolysosomal system sustains the reabsorptive activity of specialized epithelial cells. Lysosomal storage diseases such as nephropathic cystinosis cause a major dysfunction of epithelial cells lining the kidney tubule, resulting in massive losses of vital solutes in the urine. The mechanisms li...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Nat Commun
Autors principals: Festa, Beatrice Paola, Chen, Zhiyong, Berquez, Marine, Debaix, Huguette, Tokonami, Natsuko, Prange, Jenny Ann, Hoek, Glenn van de, Alessio, Cremonesi, Raimondi, Andrea, Nevo, Nathalie, Giles, Rachel H., Devuyst, Olivier, Luciani, Alessandro
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2018
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5765140/
https://ncbi.nlm.nih.gov/pubmed/29323117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-02536-7
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars