Splicing of platelet resident pre-mRNAs upon activation by physiological stimuli results in functionally relevant proteome modifications

Platelet activation triggers thrombus formation in physiological and pathological conditions, such as acute coronary syndromes. Current therapies still fail to prevent thrombotic events in numerous patients, indicating that the mechanisms modulating platelet response during activation need to be cla...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Sci Rep
Päätekijät: Nassa, Giovanni, Giurato, Giorgio, Cimmino, Giovanni, Rizzo, Francesca, Ravo, Maria, Salvati, Annamaria, Nyman, Tuula A., Zhu, Yafeng, Vesterlund, Mattias, Lehtiö, Janne, Golino, Paolo, Weisz, Alessandro, Tarallo, Roberta
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group UK 2018
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5765118/
https://ncbi.nlm.nih.gov/pubmed/29323256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-18985-5
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