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The nuclear receptor ERβ engages AGO2 in regulation of gene transcription, RNA splicing and RISC loading
BACKGROUND: The RNA-binding protein Argonaute 2 (AGO2) is a key effector of RNA-silencing pathways It exerts a pivotal role in microRNA maturation and activity and can modulate chromatin remodeling, transcriptional gene regulation and RNA splicing. Estrogen receptor beta (ERβ) is endowed with oncosu...
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| Pubblicato in: | Genome Biol |
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| Autori principali: | , , , , , , , , , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BioMed Central
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5634881/ https://ncbi.nlm.nih.gov/pubmed/29017520 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-017-1321-0 |
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