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Optimizing human Treg immunotherapy by Treg subset selection and E-selectin ligand expression
While human Tregs hold immense promise for immunotherapy, their biologic variability poses challenges for clinical use. Here, we examined clinically-relevant activities of defined subsets of freshly-isolated and culture-expanded human PBMC-derived Tregs. Unlike highly suppressive but plastic memory...
Enregistré dans:
| Publié dans: | Sci Rep |
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| Auteurs principaux: | , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group UK
2018
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5765004/ https://ncbi.nlm.nih.gov/pubmed/29323143 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-17981-z |
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