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Dysbiosis-associated change in host metabolism generates lactate to support Salmonella growth

During Salmonella-induced gastroenteritis, mucosal inflammation creates a niche that favors the expansion of the pathogen population over the microbiota. Here, we show that S. Typhimurium infection was accompanied by dysbiosis, decreased butyrate levels, and substantially elevated lactate levels in...

詳細記述

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書誌詳細
出版年:Cell Host Microbe
主要な著者: Gillis, Caroline C., Hughes, Elizabeth R., Spiga, Luisella, Winter, Maria G., Zhu, Wenhan, de Carvalho, Tatiane Furtado, Chanin, Rachael, Behrendt, Cassie L., Hooper, Lora V., Santos, Renato L., Winter, Sebastian E.
フォーマット: Artigo
言語:Inglês
出版事項: 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5764812/
https://ncbi.nlm.nih.gov/pubmed/29276172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2017.11.006
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