Dysbiosis-associated change in host metabolism generates lactate to support Salmonella growth

During Salmonella-induced gastroenteritis, mucosal inflammation creates a niche that favors the expansion of the pathogen population over the microbiota. Here, we show that S. Typhimurium infection was accompanied by dysbiosis, decreased butyrate levels, and substantially elevated lactate levels in...

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Detalhes bibliográficos
Publicado no:Cell Host Microbe
Main Authors: Gillis, Caroline C., Hughes, Elizabeth R., Spiga, Luisella, Winter, Maria G., Zhu, Wenhan, de Carvalho, Tatiane Furtado, Chanin, Rachael, Behrendt, Cassie L., Hooper, Lora V., Santos, Renato L., Winter, Sebastian E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5764812/
https://ncbi.nlm.nih.gov/pubmed/29276172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2017.11.006
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