Dysbiosis-associated change in host metabolism generates lactate to support Salmonella growth

During Salmonella-induced gastroenteritis, mucosal inflammation creates a niche that favors the expansion of the pathogen population over the microbiota. Here, we show that S. Typhimurium infection was accompanied by dysbiosis, decreased butyrate levels, and substantially elevated lactate levels in...

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Bibliografske podrobnosti
izdano v:Cell Host Microbe
Main Authors: Gillis, Caroline C., Hughes, Elizabeth R., Spiga, Luisella, Winter, Maria G., Zhu, Wenhan, de Carvalho, Tatiane Furtado, Chanin, Rachael, Behrendt, Cassie L., Hooper, Lora V., Santos, Renato L., Winter, Sebastian E.
Format: Artigo
Jezik:Inglês
Izdano: 2017
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5764812/
https://ncbi.nlm.nih.gov/pubmed/29276172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2017.11.006
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