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Poly(I:C) priming exacerbates cecal ligation and puncture-induced polymicrobial sepsis in mice

Sepsis continues to be a major healthcare issue with one of the highest mortality rates in the intensive care units. Toll-like receptors are pattern recognition receptors that are intricately involved in the pathogenesis of sepsis. TLR3 is a major receptor for double-stranded RNA and is largely asso...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Inflammation
Hauptverfasser: Sharma, Deepika, Malik, Ankit, Packiriswamy, Nandakumar, Steury, Michael D., Parameswaran, Narayanan
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5764795/
https://ncbi.nlm.nih.gov/pubmed/29127663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10753-017-0690-6
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