Blockade of CD137 Signaling Counteracts Polymicrobial Sepsis Induced by Cecal Ligation and Puncture

Sepsis, a leading cause of death worldwide, involves proinflammatory responses and inefficient bacterial clearance. Previously, we have shown that CD137 (4-1BB), a member of the tumor necrosis factor receptor superfamily, plays critical roles in eradicating infective Listeria monocytogenes, a gram-p...

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Detalles Bibliográficos
Main Authors: Nguyen, Quang-Tam, Ju, Seong-A, Park, Sang-Min, Lee, Sang-Chul, Yagita, Hideo, Lee, In Hee, Kim, Byung-Sam
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 2009
Assuntos:
Host Response and Inflammation
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2738050/
https://ncbi.nlm.nih.gov/pubmed/19564374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00407-09
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