Sarin (GB, O-isopropyl methylphosphonofluoridate) neurotoxicity: critical review

Sarin (GB, O-isopropyl methylphosphonofluoridate) is a potent organophosphorus (OP) nerve agent that inhibits acetylcholinesterase (AChE) irreversibly. The subsequent build-up of acetylcholine (ACh) in the central nervous system (CNS) provokes seizures and, at sufficient doses, centrally-mediated re...

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Detaylı Bibliyografya
Yayımlandı:Crit Rev Toxicol
Asıl Yazarlar: Abou-Donia, Mohamed B., Siracuse, Briana, Gupta, Natasha, Sokol, Ashly Sobel
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2016
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5764759/
https://ncbi.nlm.nih.gov/pubmed/27705071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10408444.2016.1220916
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