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Sarin (GB, O-isopropyl methylphosphonofluoridate) neurotoxicity: critical review
Sarin (GB, O-isopropyl methylphosphonofluoridate) is a potent organophosphorus (OP) nerve agent that inhibits acetylcholinesterase (AChE) irreversibly. The subsequent build-up of acetylcholine (ACh) in the central nervous system (CNS) provokes seizures and, at sufficient doses, centrally-mediated re...
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| Publicado no: | Crit Rev Toxicol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5764759/ https://ncbi.nlm.nih.gov/pubmed/27705071 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10408444.2016.1220916 |
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