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Sculpting ion channel functional expression with engineered ubiquitin ligases
The functional repertoire of surface ion channels is sustained by dynamic processes of trafficking, sorting, and degradation. Dysregulation of these processes underlies diverse ion channelopathies including cardiac arrhythmias and cystic fibrosis. Ubiquitination powerfully regulates multiple steps i...
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| 出版年: | eLife |
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| 主要な著者: | , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
eLife Sciences Publications, Ltd
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5764571/ https://ncbi.nlm.nih.gov/pubmed/29256394 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.29744 |
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