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Reversed graph embedding resolves complex single-cell trajectories

Single-cell trajectories can unveil how gene regulation governs cell fate decisions. However, learning the structure of complex trajectories with two or more branches remains a challenging computational problem. We present Monocle 2, which uses reversed graph embedding to describe multiple fate deci...

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Dades bibliogràfiques
Publicat a:Nat Methods
Autors principals: Qiu, Xiaojie, Mao, Qi, Tang, Ying, Wang, Li, Chawla, Raghav, Pliner, Hannah A., Trapnell, Cole
Format: Artigo
Idioma:Inglês
Publicat: 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5764547/
https://ncbi.nlm.nih.gov/pubmed/28825705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.4402
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