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An Integrated Mathematical Epithelial Cell Model for Airway Surface Liquid Regulation by Mechanical Forces

A robust method based on reverse engineering was utilized to construct the ion-channel conductance functions for airway epithelial sodium channels (ENaC), the cystic fibrosis transmembrane conductance regulator (CFTR), and calcium-activated chloride channels (CaCC). The ion-channel conductance model...

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Detalles Bibliográficos
Publicado en:J Theor Biol
Autores principales: Wu, Dan, Boucher, Richard C., Button, Brian, Elston, Timothy, Lin, Ching-Long
Formato: Artigo
Lenguaje:Inglês
Publicado: 2017
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5764545/
https://ncbi.nlm.nih.gov/pubmed/29154907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jtbi.2017.11.010
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