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Synthesis, characterization and in vitro antitrypanosomal activities of new carboxamides bearing quinoline moiety

The reported toxicities of current antitrypanosomal drugs and the emergence of drug resistant trypanosomes underscore the need for the development of new antitrypanosomal agents. We report herein the synthesis and antitrypanosomal activity of 24 new amide derivatives of 3-aminoquinoline, bearing sub...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Ugwu, David Izuchukwu, Okoro, Uchechukwu Chris, Mishra, Narendra Kumar
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5764481/
https://ncbi.nlm.nih.gov/pubmed/29324817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0191234
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